The Rules of Immunity: What Decides T Cell Fate

T cells are positioned at the frontline of the body’s immune system to fight infection, cancer, and autoimmune disease. While different subtypes of T cells exist, how these cells take their different forms has remained elusive. 

Now, a multi-institutional team of researchers led by Yale School of Medicine (YSM) has added clarity to the complex, dynamic molecular interactions that occur in the human immune system. In a new study, the researchers have identified one of the levers that controls the fate of T cells and what subtype they transform into. Their findings were published recently in the journal Science.

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